SCHEMBL1939612

SCHEMBL1939612

O=C(CF)CCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL10961112 0.97
SCHEMBL88444 0.76
SCHEMBL30570 0.76
Fluoride SCHEMBL27659500 0.72
Methane SCHEMBL9114544 0.72
Hydrochloric Acid SCHEMBL341033 0.72
SCHEMBL4805121 0.72
Hydrochloric Acid SCHEMBL308872 0.72
Water SCHEMBL20546842 0.72
Chloroacetic Acid SCHEMBL28421118 0.71 TSHR (0.71)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0872468-B1 Method for producing 3,3-dichloro-1,1,1-trifluoroacetone CENTRAL GLASS CO LTD (JP) 2001-07-25 EP claimed
US-6177595-B1 FLUORINATING IN A LIQUID PHASE A 1,1-DICHLORO-3-FLUORO-3,3-DICHLORO-, CHLORO/FLUORO-, OR DIFLUOROACETONE, PREFERABLY PENTACHLOROACETONE, BY HYDROGEN FLUORIDE USING A CATALYST OF TIN TETRAHALIDE; CORROSION RESISTANCE; EFFICIENCY CENTRAL GLASS COMPANY, LIMITED (JP) 2001-01-23 US claimed
US-5905174-A FLUORINATING PENTACHLOROACETONE WITH HYDROGEN FLUORIDE IN THE PRESENCE OF A CATALYST CENTRAL GLASS COMPANY, LIMITED (JP) 1999-05-18 US claimed
EP-0872468-A1 Method for producing 3,3-dichloro-1,1,1-trifluoroacetone Central Glass Company, Limited (JP) 1998-10-21 EP claimed
EP-0146464-B1 CATALYTIC PROCESS FOR THE PREPARATION OF HEXAFLUORACETONE ELF ATOCHEM S.A. (FR) 1986-11-05 EP claimed
US-4579974-A Catalytic process for the preparation of hexafluoroacetone ATOCHEM (FR) 1986-04-01 US claimed
EP-0146464-A2 Catalytic process for the preparation of hexafluoracetone ELF ATOCHEM S.A. (FR) 1985-06-26 EP claimed
US-4386223-A Method of purifying hexafluoroacetone containing chlorofluoroacetones CENTRAL GLASS COMPANY LIMITED (JP) 1983-05-31 US claimed
JP-10330308-A None JP disclosed
JP-57081433-A None JP disclosed
JP-59204149-A None JP disclosed
CN-120058811-A Cobalt metal complex and preparation method and application thereof 浙江诺亚氟化工有限公司 2025-05-30 CN disclosed
CN-115894191-B Method for coproducing trifluoroacetone and difluoroacetate 山东华安新材料有限公司 2024-01-30 CN disclosed
CN-115894191-A Method for co-producing trifluoroacetone and difluoroacetic acid ester 山东华安新材料有限公司 2023-04-04 CN disclosed
JP-S59204149-A METHOD FOR PURIFYING HEXAFLUOROACETONE HYDRATE CENTRAL GLASS CO LTD 1984-11-19 JP disclosed
US-4386223-A Method of purifying hexafluoroacetone containing chlorofluoroacetones CENTRAL GLASS COMPANY LIMITED (JP) 1983-05-31 US disclosed
US-4386223-A Method of purifying hexafluoroacetone containing chlorofluoroacetones CENTRAL GLASS COMPANY LIMITED (JP) 1983-05-31 US disclosed
US-4386223-A Method of purifying hexafluoroacetone containing chlorofluoroacetones CENTRAL GLASS COMPANY LIMITED (JP) 1983-05-31 US disclosed
JP-S5781433-A PURIFICATION OF HEXAFLUOROACETONE CENTRAL GLASS CO LTD 1982-05-21 JP disclosed
US-4028356-A Triazinobenzodiazepines THE UPJOHN COMPANY (US) 1977-06-07 US disclosed