SCHEMBL1939726

SCHEMBL1939726

Cc1[c]c(-c2ccccc2Cl)[nH]n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.46
POLB P06746 2/20 0.46
HSD11B1 P28845 2/20 0.42
IDO1 P14902 1/20 0.41
NOTUM Q6P988 1/20 0.40
DCUN1D1 Q96GG9 1/20 0.40
NR1H2 P55055 2/20 0.40
NR1H3 Q13133 2/20 0.40
LDHA P00338 1/20 0.40
SMN1; SMN2 Q16637 5/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
ALDH1A1 P00352 4/20 0.39
HPGD P15428 4/20 0.39
TP53 P04637 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
ALOX15 P16050 2/20 0.39
NFKB1 P19838 2/20 0.39
NFKB2 Q00653 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4637043 0.78 KMT2A (0.39) KMT2APOLBHSD11B1IDO1NOTUM
SCHEMBL1939739 0.78 KMT2A (0.39) KMT2APOLBHSD11B1IDO1NOTUM
SCHEMBL3629536 0.78 KMT2A (0.39) KMT2APOLBHSD11B1IDO1NOTUM
SCHEMBL1940371 0.75 GRM4 (0.35)
SCHEMBL3630044 0.73 AKT2 (0.42) KMT2APOLBIDO1DCUN1D1NR1H2
SCHEMBL4637112 0.71 KMT2A (0.46) KMT2APOLBHSD11B1IDO1NOTUM
SCHEMBL7857088 0.69 IKBKE (0.49) POLBIDO1NOTUMALDH1A1HPGD
SCHEMBL29059206 0.67 KMT2A (0.44) KMT2APOLBHSD11B1IDO1NOTUM
SCHEMBL2614354 0.66 NPC1 (0.64) KMT2APOLBIDO1LDHASMN1; SMN2
SCHEMBL12523392 0.66 KMT2A (0.51) KMT2APOLBHSD11B1IDO1NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937664-B1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2011-06-15 EP disclosed
EP-2144898-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2010-01-20 EP disclosed
WO-2008130021-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 WO disclosed
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed