SCHEMBL4637112

SCHEMBL4637112

Cc1[c]c(-c2ccccc2Cl)n[nH]1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.46
POLB P06746 2/20 0.46
NR1H2 P55055 2/20 0.43
NR1H3 Q13133 2/20 0.43
HSD11B1 P28845 2/20 0.42
IDO1 P14902 1/20 0.41
NOTUM Q6P988 1/20 0.40
DCUN1D1 Q96GG9 1/20 0.40
LDHA P00338 1/20 0.40
SMN1; SMN2 Q16637 5/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
ALDH1A1 P00352 4/20 0.39
HPGD P15428 3/20 0.39
TP53 P04637 2/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
ALOX15 P16050 2/20 0.39
NFKB1 P19838 2/20 0.39
NFKB2 Q00653 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4636906 0.78 KMT2A (0.39) KMT2APOLBNR1H2NR1H3HSD11B1
SCHEMBL4637555 0.78 KMT2A (0.39) KMT2APOLBNR1H2NR1H3HSD11B1
SCHEMBL4637026 0.78 NR1H2 (0.40) KMT2APOLBNR1H2NR1H3HSD11B1
SCHEMBL3625480 0.75 GRM4 (0.35) ALDH1A1GAACYP2A6
SCHEMBL1939726 0.71 KMT2A (0.46) KMT2APOLBNR1H2NR1H3HSD11B1
SCHEMBL3629536 0.68 KMT2A (0.39) KMT2APOLBNR1H2NR1H3HSD11B1
SCHEMBL1086652 0.68 PTGS1 (0.47) KMT2APOLBHSD11B1SMN1; SMN2NPC1
SCHEMBL3632831 0.68 BTK (0.46) POLBSMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL15637594 0.67 IDO1 (0.39) KMT2APOLBHSD11B1IDO1DCUN1D1
SCHEMBL12523392 0.66 KMT2A (0.51) KMT2APOLBNR1H2NR1H3HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed