SCHEMBL19398249

SCHEMBL19398249

C=C(C)C(=O)OCCC[Si](C)(C)O[Si](C)(C)CC[Si](C)(O[Si](O[Si](O[Si](O[Si](C)(CC[Si](C)(C)O[Si](C)(C)CCCOC(=O)C(=C)C)c1ccccc1)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TSHR P16473 2/20 0.35
THRB P10828 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19398253 1.00 POLB (0.39) POLBAPEX1HTTTDP1TSHR
SCHEMBL19398251 0.92 POLB (0.34) POLBAPEX1HTTTDP1TSHR
SCHEMBL17061426 0.90 TDP1 (0.44) POLBAPEX1HTTTDP1TSHR
SCHEMBL19398252 0.88 POLB (0.33) POLBAPEX1HTTTDP1
SCHEMBL26282522 0.86 TDP1 (0.41) POLBAPEX1HTTTDP1TSHR
SCHEMBL9763744 0.86 TDP1 (0.41) POLBAPEX1HTTTDP1TSHR
SCHEMBL9764044 0.83 TDP1 (0.45) POLBAPEX1HTTTDP1TSHR
SCHEMBL25755693 0.83 POLB (0.39) POLBAPEX1HTTTDP1TSHR
SCHEMBL19718526 0.82 POLB (0.39) POLBAPEX1HTTTDP1TSHR
SCHEMBL13863107 0.82 TDP1 (0.44) POLBAPEX1HTTTDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170275406-A1 UV CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, OPTICAL ELEMENT ENCAPSULATION MATERIAL COMPRISED OF THE COMPOSITION, AND OPTICAL ELEMENT ENCAPSULATED BY THE ENCAPSULATION MATERIAL SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-09-28 US disclosed