Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17061426 | 0.96 | TDP1 (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL25755693 | 0.90 | POLB (0.39) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL19718526 | 0.89 | POLB (0.39) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL25755577 | 0.88 | TDP1 (0.41) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL9764044 | 0.87 | TDP1 (0.45) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL19398249 | 0.86 | POLB (0.39) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL19398253 | 0.86 | POLB (0.39) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL2367678 | 0.86 | TDP1 (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL17061428 | 0.86 | TDP1 (0.44) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL1398279 | 0.86 | TDP1 (0.44) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4988788-A | Room temperature-curable coating composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-01-29 | — | — | US | claimed |