Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395999 | 0.97 | — | — | |
| SCHEMBL13337341 | 0.89 | BTN3A1 (0.41) | BTN3A1HSD17B10THRBMEN1KMT2A | |
| SCHEMBL18040259 | 0.89 | BTN3A1 (0.41) | BTN3A1HSD17B10THRBMEN1KMT2A | |
| SCHEMBL662434 | 0.87 | BTN3A1 (0.43) | BTN3A1HSD17B10THRBMEN1KMT2A | |
| SCHEMBL28094975 | 0.85 | THRB (0.48) | BTN3A1THRBTSHREPHX1ALDH1A1 | |
| SCHEMBL6883385 | 0.83 | TSHR (0.52) | BTN3A1THRBMEN1HTTKMT2A | |
| SCHEMBL9396015 | 0.81 | HTT (0.50) | THRBMEN1HTTKMT2AMAPT | |
| SCHEMBL10044435 | 0.80 | MEN1 (0.55) | BTN3A1THRBMEN1HTTKMT2A | |
| SCHEMBL28723527 | 0.80 | BTN3A1 (0.36) | BTN3A1THRBEPHX1 | |
| SCHEMBL28723557 | 0.80 | BTN3A1 (0.36) | BTN3A1THRBEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162663-A1 | PRODRUGS OF CYTOTOXIC ACTIVE AGENTS HAVING ENZYMATICALLY CLEAVABLE GROUPS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |