Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19403325 | 1.00 | KCNH2 (0.31) | KCNH2ATMATR | |
| SCHEMBL29676364 | 1.00 | KCNH2 (0.31) | KCNH2ATMATR | |
| SCHEMBL22714773 | 1.00 | KCNH2 (0.31) | KCNH2ATMATR | |
| SCHEMBL19403089 | 1.00 | KCNH2 (0.31) | KCNH2ATMATR | |
| SCHEMBL19403326 | 1.00 | KCNH2 (0.31) | KCNH2ATMATR | |
| SCHEMBL22714771 | 1.00 | KCNH2 (0.31) | KCNH2ATMATR | |
| SCHEMBL26952978 | 0.81 | F11 (0.31) | — | |
| SCHEMBL24376990 | 0.76 | CASR (0.45) | — | |
| SCHEMBL16044206 | 0.76 | CASR (0.44) | — | |
| SCHEMBL16044205 | 0.76 | CASR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162611-A1 | QUINOLINE-3-CARBOXAMIDE COMPOUNDS AND THEIR USE IN TREATING CANCER | ASTRAZENECA AB (SE) | 2017-09-28 | — | — | WO | disclosed |