Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887078 | 1.00 | REN (0.52) | RENPDE4B | |
| SCHEMBL1940321 | 1.00 | REN (0.52) | RENPDE4B | |
| SCHEMBL1941728 | 1.00 | REN (0.52) | RENPDE4B | |
| SCHEMBL1941709 | 0.95 | REN (0.55) | RENPDE4B | |
| SCHEMBL1943045 | 0.93 | REN (0.56) | RENPDE4B | |
| SCHEMBL1942427 | 0.91 | REN (0.50) | RENPDE4B | |
| SCHEMBL1941800 | 0.91 | REN (0.50) | RENPDE4B | |
| SCHEMBL1941796 | 0.91 | REN (0.50) | RENPDE4B | |
| SCHEMBL1942041 | 0.89 | REN (0.59) | RENPDE4B | |
| SCHEMBL1941811 | 0.89 | REN (0.59) | RENPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1175400-B1 | RENIN INHIBITORS | HOFFMANN LA ROCHE (CH) | 2011-06-15 | — | — | EP | disclosed |