Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.60 |
| ▸ | ITGAV | P06756 | 20/20 | 0.60 |
| ▸ | ITGB5 | P18084 | 20/20 | 0.60 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.60 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.54 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23308999 | 0.87 | ITGAV (0.59) | ITGB3ITGAVITGB5ITGB1ITGB6 | |
| SCHEMBL17629344 | 0.84 | ITGB3 (0.72) | ITGB3ITGAVITGB5ITGB1 | |
| SCHEMBL20305086 | 0.84 | ITGB3 (0.72) | ITGB3ITGAVITGB5ITGB1 | |
| SCHEMBL21937505 | 0.82 | ITGAV (0.54) | ITGB3ITGAVITGB5ITGB1ITGB6 | |
| SCHEMBL22043499 | 0.82 | ITGAV (0.53) | ITGB3ITGAVITGB5ITGB1ITGB6 | |
| SCHEMBL20904207 | 0.81 | ITGAV (0.57) | ITGB3ITGAVITGB5ITGB1ITGB6 | |
| SCHEMBL19384558 | 0.81 | ITGAV (0.59) | ITGB3ITGAVITGB5ITGB1ITGB6 | |
| SCHEMBL17633618 | 0.81 | ITGAV (0.59) | ITGB3ITGAVITGB5ITGB1ITGB6 | |
| SCHEMBL17633617 | 0.81 | ITGAV (0.59) | ITGB3ITGAVITGB5ITGB1ITGB6 | |
| SCHEMBL22110205 | 0.80 | ITGAV (0.54) | ITGB3ITGAVITGB5ITGB1ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162570-A1 | NAPHTHYRIDINES AS INTEGRIN ANTAGONISTS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-09-28 | — | — | WO | disclosed |