Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 13/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 13/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404284 | 0.85 | BCL9 (0.52) | BCL9CTNNB1KCNH2 | |
| SCHEMBL19703138 | 0.83 | SLC6A2 (0.50) | BCL9CTNNB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22278201 | 0.83 | SLC6A2 (0.50) | BCL9CTNNB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22278185 | 0.83 | SLC6A2 (0.50) | BCL9CTNNB1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL22265856 | 0.82 | SLC6A2 (0.49) | BCL9CTNNB1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL22265673 | 0.82 | SLC6A2 (0.49) | BCL9CTNNB1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL594232 | 0.81 | KMT2A (0.47) | KCNH2 | |
| SCHEMBL593140 | 0.80 | KMT2A (0.46) | KCNH2 | |
| SCHEMBL20165032 | 0.78 | ALDH1A1 (0.57) | — | |
| SCHEMBL20165033 | 0.78 | ALDH1A1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017165839-A1 | METHODS AND COMPOSITION OF 4-SUBSTITUTED BENZOYLPIPERAZINE-1-SUBSTITUTED CARBONYLS AS BETA-CATENIN/B-CELL LYMPHOMA 9 INHIBITORS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2017-09-28 | — | — | WO | disclosed |