Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 13/20 | 0.75 |
| ▸ | BRPF1 | P55201 | 13/20 | 0.75 |
| ▸ | TAF1 | P21675 | 13/20 | 0.75 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 3/20 | 0.46 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404464 | 0.85 | BRD1 (1.00) | BRD1BRPF1TAF1MEN1RGS12 | |
| SCHEMBL19404830 | 0.81 | TAF1 (0.51) | BRD1BRPF1TAF1MEN1USP2 | |
| SCHEMBL19404591 | 0.81 | BRD1 (0.71) | BRD1BRPF1TAF1POLBMAPT | |
| SCHEMBL19404528 | 0.81 | BRD1 (0.71) | BRD1BRPF1TAF1MAPK1TLR9 | |
| SCHEMBL19405039 | 0.81 | TAF1 (0.61) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404459 | 0.78 | BRD1 (0.73) | BRD1BRPF1TAF1MEN1USP2 | |
| SCHEMBL19404629 | 0.78 | TAF1 (0.75) | BRD1BRPF1TAF1MEN1USP2 | |
| SCHEMBL19404605 | 0.78 | TAF1 (0.49) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404455 | 0.77 | BRD1 (0.74) | BRD1BRPF1TAF1MEN1USP2 | |
| SCHEMBL19404628 | 0.76 | TAF1 (0.59) | BRD1BRPF1TAF1BRD4TAF1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162661-A1 | 1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |