Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 15/20 | 0.71 |
| ▸ | BRPF1 | P55201 | 15/20 | 0.71 |
| ▸ | TAF1 | P21675 | 15/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.48 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19405013 | 0.91 | TAF1 (0.61) | BRD1BRPF1TAF1KDM4EALDH1A1 | |
| SCHEMBL19404590 | 0.88 | TAF1 (0.57) | BRD1BRPF1TAF1KDM4EALDH1A1 | |
| SCHEMBL19404528 | 0.87 | BRD1 (0.71) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404459 | 0.84 | BRD1 (0.73) | BRD1BRPF1TAF1KDM4EALDH1A1 | |
| SCHEMBL19404593 | 0.83 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404455 | 0.83 | BRD1 (0.74) | BRD1BRPF1TAF1ALDH1A1HPGD | |
| SCHEMBL19405012 | 0.83 | KDM4E (0.59) | BRD1BRPF1TAF1KDM4EALDH1A1 | |
| SCHEMBL19404507 | 0.82 | TAF1 (0.58) | BRD1BRPF1TAF1KDM4EALDH1A1 | |
| SCHEMBL19404629 | 0.81 | TAF1 (0.75) | BRD1BRPF1TAF1ALDH1A1BRD4 | |
| SCHEMBL19404460 | 0.81 | BRD1 (0.75) | BRD1BRPF1TAF1BRD4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162661-A1 | 1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |