Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 17/20 | 0.63 |
| ▸ | BRPF1 | P55201 | 16/20 | 0.47 |
| ▸ | TAF1 | P21675 | 16/20 | 0.47 |
| ▸ | BRD4 | O60885 | 3/20 | 0.45 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.45 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404818 | 0.86 | BRD1 (0.60) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404604 | 0.85 | BRD1 (0.58) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404433 | 0.81 | BRD1 (0.69) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19405011 | 0.81 | BRD1 (0.69) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404498 | 0.81 | BRD1 (0.69) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404454 | 0.81 | BRD1 (0.64) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404447 | 0.80 | BRD1 (0.60) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404624 | 0.80 | BRD1 (0.66) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404451 | 0.79 | BRD1 (0.59) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404791 | 0.79 | KDM4E (0.65) | BRD1BRPF1TAF1BRD4TAF1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162661-A1 | 1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |