Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 15/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 15/20 | 0.39 |
| ▸ | TAF1 | P21675 | 14/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | HBB | P68871 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.38 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404607 | 0.87 | BRD1 (0.45) | BRD1BRPF1TAF1MEN1KMT2A | |
| SCHEMBL19404611 | 0.80 | BRD1 (0.63) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404610 | 0.76 | BRD1 (0.46) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404621 | 0.75 | BRD1 (0.52) | BRD1BRPF1TAF1MEN1KMT2A | |
| SCHEMBL19404816 | 0.74 | BRD1 (0.61) | BRD1BRPF1TAF1MEN1KMT2A | |
| SCHEMBL19405034 | 0.72 | BRD1 (0.67) | BRD1BRPF1TAF1MEN1KMT2A | |
| SCHEMBL19404474 | 0.72 | MEN1 (0.47) | BRD1BRPF1TAF1MEN1KMT2A | |
| SCHEMBL14918648 | 0.67 | TYMS (0.47) | MEN1KMT2AUSP2ALDH1A1MAPT | |
| SCHEMBL19404606 | 0.66 | BRD1 (0.66) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404856 | 0.65 | BRD1 (0.63) | BRD1BRPF1TAF1BRD4TAF1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162661-A1 | 1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |