Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 12/20 | 0.67 |
| ▸ | BRPF1 | P55201 | 12/20 | 0.67 |
| ▸ | TAF1 | P21675 | 11/20 | 0.67 |
| ▸ | BRD4 | O60885 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | USP2 | O75604 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CASP1 | P29466 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.39 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.39 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19404621 | 0.84 | BRD1 (0.52) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19405036 | 0.81 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4 | |
| SCHEMBL19405033 | 0.78 | BRD1 (0.77) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404480 | 0.73 | BRD1 (0.49) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404607 | 0.73 | BRD1 (0.45) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404612 | 0.72 | BRD1 (0.39) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404816 | 0.71 | BRD1 (0.61) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404457 | 0.69 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4 | |
| SCHEMBL19405041 | 0.68 | BRD1 (0.67) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19405037 | 0.68 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162661-A1 | 1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |