Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD1 | O95696 | 16/20 | 0.74 |
| ▸ | BRPF1 | P55201 | 16/20 | 0.74 |
| ▸ | TAF1 | P21675 | 14/20 | 0.74 |
| ▸ | BRD4 | O60885 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TAF1L | Q8IZX4 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.44 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19405059 | 0.90 | BRD1 (0.70) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404511 | 0.85 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19405003 | 0.77 | BRD1 (0.74) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404510 | 0.77 | BRD1 (0.72) | BRD1BRPF1TAF1BRD4POLB | |
| SCHEMBL13893856 | 0.74 | CYP1B1 (0.71) | BRD1BRPF1TAF1POLBMEN1 | |
| SCHEMBL19404530 | 0.74 | BRD1 (0.52) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404615 | 0.74 | TAF1 (0.79) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404501 | 0.74 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L | |
| SCHEMBL19404837 | 0.73 | BRD1 (0.54) | BRD1BRPF1TAF1BRD4MEN1 | |
| SCHEMBL19404815 | 0.72 | BRD1 (1.00) | BRD1BRPF1TAF1BRD4TAF1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017162661-A1 | 1H-BENZO[DE]ISOQUINOLINE-1,3(2H)-DIONES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-28 | — | — | WO | disclosed |