Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.78 |
| ▸ | TLR9 | Q9NR96 | 8/20 | 0.56 |
| ▸ | SPIN1 | Q9Y657 | 3/20 | 0.47 |
| ▸ | SPIN4 | Q56A73 | 1/20 | 0.47 |
| ▸ | SPIN3 | Q5JUX0 | 1/20 | 0.47 |
| ▸ | SPIN2B | Q9BPZ2 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.46 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.45 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19405236 | 0.90 | TLR7 (0.78) | TLR7TLR9SPIN1SPIN4SPIN3 | |
| SCHEMBL19405149 | 0.88 | TLR7 (1.00) | TLR7TLR9PDGFRBPDGFRANTSR1 | |
| SCHEMBL19405237 | 0.83 | TLR9 (0.81) | TLR7TLR9PDGFRBPDGFRAEHMT2 | |
| SCHEMBL19406427 | 0.78 | TLR7 (0.80) | TLR7TLR9SPIN1 | |
| SCHEMBL19406161 | 0.78 | TLR7 (0.63) | TLR7TLR9SPIN1EHMT2 | |
| SCHEMBL19385129 | 0.78 | TLR7 (1.00) | TLR7TLR9SPIN1SPIN4SPIN3 | |
| SCHEMBL19405151 | 0.78 | TLR7 (1.00) | TLR7TLR9EHMT2 | |
| SCHEMBL19405193 | 0.73 | TLR9 (0.80) | TLR7TLR9PDGFRBPDGFRANTSR1 | |
| SCHEMBL20838528 | 0.73 | TLR7 (0.75) | TLR7TLR9NTSR1 | |
| SCHEMBL4234622 | 0.73 | EHMT2 (0.50) | TLR7EHMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017163264-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | disclosed |