Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 14/20 | 1.00 |
| ▸ | TLR9 | Q9NR96 | 11/20 | 0.87 |
| ▸ | SPIN1 | Q9Y657 | 3/20 | 0.54 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | SPIN4 | Q56A73 | 1/20 | 0.53 |
| ▸ | SPIN3 | Q5JUX0 | 1/20 | 0.53 |
| ▸ | SPIN2B | Q9BPZ2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19385236 | 0.93 | TLR7 (1.00) | TLR7TLR9SPIN1EHMT2SPIN4 | |
| SCHEMBL29937017 | 0.86 | TLR7 (1.00) | TLR7TLR9SPIN1EHMT2SPIN4 | |
| SCHEMBL19385205 | 0.86 | TLR7 (1.00) | TLR7TLR9SPIN1EHMT2SPIN4 | |
| SCHEMBL19385401 | 0.82 | TLR7 (0.79) | TLR7TLR9SPIN1EHMT2NSD2 | |
| SCHEMBL19405236 | 0.82 | TLR7 (0.78) | TLR7TLR9SPIN1EHMT2NSD2 | |
| SCHEMBL19385009 | 0.81 | TLR7 (1.00) | TLR7TLR9SPIN1EHMT2NSD2 | |
| SCHEMBL19405214 | 0.81 | TLR7 (1.00) | TLR7TLR9SPIN1 | |
| SCHEMBL19385103 | 0.81 | TLR7 (1.00) | TLR7TLR9SPIN1EHMT2 | |
| SCHEMBL19405239 | 0.78 | TLR7 (0.78) | TLR7TLR9SPIN1EHMT2SPIN4 | |
| SCHEMBL22401497 | 0.78 | TLR9 (1.00) | TLR7TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3433249-B1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL SCIENT IND RES (IN) | 2022-11-09 | — | — | EP | disclosed |
| US-10662177-B2 | Blocking toll-like receptor 9 signaling with small molecule antagonist | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-05-26 | — | — | US | disclosed |
| US-10662177-B2 | Blocking toll-like receptor 9 signaling with small molecule antagonist | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-05-26 | — | — | US | disclosed |
| US-20190092758-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2019-03-28 | — | — | US | disclosed |
| US-20190092758-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2019-03-28 | — | — | US | disclosed |
| EP-3433249-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | Council Of Scientific & Industrial Research (IN) | 2019-01-30 | — | — | EP | disclosed |
| WO-2017163264-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | disclosed |
| WO-2017163264-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190092758-A1 | BLOCKING TOLL-LIKE RECEPTOR 9 SIGNALING WITH SMALL MOLECULE ANTAGONIST | TLR9, TLR1, TLR3 | TLR7 5/4885TLR9 1/4885SPIN1 4310/4885 |
| US-10662177-B2 | Blocking toll-like receptor 9 signaling with small molecule antagonist | TLR9, TLR1, TLR3 | TLR7 4/4885TLR9 1/4885SPIN1 4423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.