Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11584178 | 0.79 | PTGS1 (0.36) | PTGS1SLC7A11ENPEPFOLH1KDM4E | |
| SCHEMBL7150005 | 0.79 | PTGS1 (0.36) | PTGS1SLC7A11ENPEPFOLH1KDM4E | |
| SCHEMBL11585164 | 0.78 | — | — | |
| SCHEMBL2991431 | 0.78 | — | — | |
| SCHEMBL8345827 | 0.78 | — | — | |
| SCHEMBL3315313 | 0.77 | — | — | |
| SCHEMBL3315309 | 0.77 | — | — | |
| SCHEMBL23829900 | 0.76 | CA12 (0.35) | PTGS1SLC7A11ENPEPKDM4EMAPT | |
| SCHEMBL11583564 | 0.76 | CA12 (0.35) | PTGS1SLC7A11ENPEPKDM4EMAPT | |
| SCHEMBL4409628 | 0.74 | ALDH1A1 (0.32) | PTGS1SLC7A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2629769-B1 | CYSTEINE AND AGEING-ASSOCIATED ANOREXIA | NESTEC SA (CH) | 2017-10-04 | — | — | EP | claimed |