Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22321677 | 1.00 | MEN1 (0.32) | MEN1LMNAKMT2ATDP1 | |
| SCHEMBL3482824 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL11035270 | 0.76 | — | — | |
| SCHEMBL7788961 | 0.75 | — | — | |
| SCHEMBL6139270 | 0.74 | LMNA (0.36) | MEN1LMNAKMT2ATDP1 | |
| SCHEMBL9694226 | 0.74 | LMNA (0.36) | MEN1LMNAKMT2ATDP1 | |
| SCHEMBL31286291 | 0.72 | TDP1 (0.35) | TDP1 | |
| SCHEMBL1132201 | 0.71 | — | — | |
| SCHEMBL14092582 | 0.70 | TDP1 (0.33) | TDP1 | |
| SCHEMBL8377780 | 0.70 | LMNA (0.46) | LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017163186-A1 | ALKYNYL NUCLEOSIDE ANALOGS AS INHIBITORS OF HUMAN RHINOVIRUS | NOVARTIS AG (CH) | 2017-09-28 | — | — | WO | disclosed |