Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 9/20 | 0.47 |
| ▸ | HTR2C | P28335 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3341281 | 0.93 | HTR2A (0.47) | L3MBTL1POLBHTR2AHTR2CMAPT | |
| SCHEMBL134851 | 0.83 | HTR2A (0.49) | L3MBTL1POLBHTR2AHTR2CHTR2B | |
| SCHEMBL29775360 | 0.82 | HTR2A (0.51) | L3MBTL1POLBHTR2AHTR2CHTR2B | |
| SCHEMBL19612115 | 0.82 | HTR2A (0.47) | L3MBTL1POLBHTR2AHTR2CMAPT | |
| SCHEMBL3278339 | 0.82 | HTR2A (0.51) | L3MBTL1POLBHTR2AHTR2CMAPT | |
| SCHEMBL23326154 | 0.82 | HTR2A (0.51) | L3MBTL1POLBHTR2AHTR2CHTR2B | |
| SCHEMBL31075560 | 0.80 | HTR2A (0.46) | L3MBTL1POLBHTR2AHTR2CMAPT | |
| SCHEMBL12302481 | 0.79 | HTR2A (0.49) | L3MBTL1POLBHTR2AHTR2CHTR2B | |
| SCHEMBL19627259 | 0.79 | HTR2A (0.45) | L3MBTL1POLBHTR2AHTR2CMAPT | |
| SCHEMBL23326095 | 0.78 | LMNA (0.47) | L3MBTL1POLBHTR2AHTR2CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111318-A1 | SOMATOSTATIN SUBTYPE RECEPTOR 3 (SSTR3) AGONISTS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. (US) | 2025-05-30 | — | — | WO | disclosed |
| WO-2025043094-A1 | BENZOTHIA(DIA)ZEPINE COMPOUNDS FOR TREATMENT OF HBV AND HDV | ASSEMBLY BIOSCIENCES, INC. (US) | 2025-02-27 | — | — | WO | disclosed |
| WO-2024177984-A1 | BENZOTHIA(DIA)ZEPINE COMPOUNDS FOR TREATMENT OF HBV AND HDV | ASSEMBLY BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |
| EP-3433258-B1 | PYRIMIDINES AND VARIANTS THEREOF, AND USES THEREFOR | AFFERENT PHARMACEUTICALS INC (US) | 2023-07-19 | — | — | EP | disclosed |
| WO-2017165255-A1 | PYRIMIDINES AND VARIANTS THEREOF, AND USES THEREFOR | AFFERENT PHARMACEUTICALS INC. (US) | 2017-09-28 | — | — | WO | disclosed |