SCHEMBL194085

SCHEMBL194085

C=C(C)C(=O)N(C)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.46
KMT2A Q03164 4/20 0.46
POLB P06746 1/20 0.46
KDM4E B2RXH2 1/20 0.46
RAB9A P51151 2/20 0.45
NPC1 O15118 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
FAAH O00519 1/20 0.44
PHGDH O43175 1/20 0.44
MGLL Q99685 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
LMNA P02545 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
PKM P14618 1/20 0.41
ATM Q13315 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13448239 0.88 HTT (0.44) HTTKMT2APOLBKDM4ERAB9A
SCHEMBL28379612 0.84 MAPK1 (0.53) HTTKMT2APOLBKDM4ERAB9A
SCHEMBL17704773 0.84 KMT2A (0.53) HTTKMT2APOLBKDM4ERAB9A
SCHEMBL15442018 0.83 ALDH1A1 (0.48) KMT2APOLBKDM4ERAB9ANPC1
SCHEMBL31339223 0.83 HTT (0.49) HTTKMT2APOLBKDM4ERAB9A
SCHEMBL24106352 0.82 ALDH1A1 (0.50) HTTKMT2APOLBKDM4ERAB9A
SCHEMBL4022489 0.82 KMT2A (0.44) HTTKMT2APOLBKDM4ERAB9A
SCHEMBL4889215 0.82 APP (0.38) KMT2APOLBKDM4ERAB9ANPC1
SCHEMBL195179 0.81 NPSR1 (0.54) HTTKMT2APOLBKDM4ERAB9A
SCHEMBL9456596 0.80 KMT2A (0.50) HTTKMT2APOLBKDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 930 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119372671-A Method for synthesizing amino acid compound by participation of carbon dioxide 新疆大学 2025-01-28 CN claimed
CN-118355112-A Hydrogel particles as feeder cells and as synthetic antigen presenting cells 弹弓生物科学公司 2024-07-16 CN claimed
CN-117247372-A Preparation method of oxindole compound 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) 2023-12-19 CN claimed
CN-109734564-B Method for synthesizing trifluoroethyl aromatic compound 南京理工大学 2022-09-16 CN claimed
CN-112062706-A Method for continuously preparing indolone compounds by using microchannel reaction device 南京先进生物材料与过程装备研究院有限公司 2020-12-11 CN claimed
CN-107615062-A Hydrogel particles with tunable optical properties and methods of using the same 弹弓生物科学公司 2018-01-19 CN claimed
US-8603709-B2 Polyurethane anticurl backside coating (ACBC) photoconductors XEROX CORPORATION (US) 2013-12-10 US claimed
EP-2224288-B1 PHOTOCONDUCTORS COMPRISING EPOXY CARBOXYL RESIN MIXTURE HOLE BLOCKING LAYER XEROX CORP (US) 2013-10-16 EP claimed
US-8105670-B2 Glycoluril resin and polyol resin dual members XEROX CORPORATION (US) 2012-01-31 US claimed
US-20110318679-A1 POLYURETHANE ANTICURL BACKSIDE COATING (ACBC) PHOTOCONDUCTORS XEROX CORPORATION (US) 2011-12-29 US claimed
US-20100248108-A1 GLYCOLURIL RESIN AND POLYOL RESIN DUAL MEMBERS XEROX CORPORATION (US) 2010-09-30 US claimed
US-20100221651-A1 EPOXY CARBOXYL RESIN MIXTURE HOLE BLOCKING LAYER PHOTOCONDUCTORS XEROX CORPORATION (US) 2010-09-02 US claimed
EP-2224288-A2 Epoxy carboxyl resin mixture hole blocking layer photoconductors Xerox Corporation (US) 2010-09-01 EP claimed
US-7579126-B2 Hole blocking layer containing photoconductors XEROX CORPORATION (US) 2009-08-25 US claimed
US-7504446-B2 Aqueous inks containing colored polymers XEROX CORPORATION (US) 2009-03-17 US claimed
US-20080220350-A1 Hole blocking layer containing photoconductors XEROX CORPORATION 2008-09-11 US claimed
EP-1967907-A1 Hole Blocking Layer Containing Photoconductors Xerox Corporation (US) 2008-09-10 EP claimed
US-20070248813-A1 Imaging member having styrene XEROX CORPORATION (US) 2007-10-25 US claimed
US-20060074142-A1 Aqueous inks containing colored polymers XEROX CORPORATION 2006-04-06 US claimed
US-5698361-A DIAZONIUM COMPOUND, POLYMERIC BINDER; DURABILITY FUJI PHOTO FILM CO., LTD. (JP) 1997-12-16 US claimed