Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 2/20 | 0.50 |
| ▸ | CASP7 | P55210 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HAT1 | O14929 | 2/20 | 0.50 |
| ▸ | RBBP7 | Q16576 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TST | Q16762 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22285880 | 1.00 | TDP1 (0.50) | TDP1MEN1KMT2AUSP2KDM4E | |
| SCHEMBL22285881 | 0.85 | TDP1 (0.43) | TDP1MEN1KMT2AUSP2KDM4E | |
| SCHEMBL19411273 | 0.84 | MEN1 (0.45) | TDP1MEN1KMT2AUSP2KDM4E | |
| SCHEMBL22285875 | 0.84 | MEN1 (0.45) | TDP1MEN1KMT2AUSP2KDM4E | |
| SCHEMBL19411266 | 0.84 | KMT2A (0.47) | TDP1MEN1KMT2AUSP2KDM4E | |
| SCHEMBL19411259 | 0.84 | TDP1 (0.47) | TDP1MEN1KMT2AUSP2KDM4E | |
| SCHEMBL22285876 | 0.84 | KMT2A (0.47) | TDP1MEN1KMT2AUSP2KDM4E | |
| SCHEMBL22285882 | 0.84 | TDP1 (0.47) | TDP1MEN1KMT2AUSP2KDM4E | |
| SCHEMBL19411274 | 0.83 | KDM4E (0.44) | TDP1MEN1KMT2AUSP2KDM4E | |
| SCHEMBL22285879 | 0.83 | KDM4E (0.44) | TDP1MEN1KMT2AUSP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11002524-B2 | Cyclic compounds and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-05-11 | — | — | US | claimed |
| US-20200249002-A9 | A CYCLIC COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-08-06 | — | — | US | claimed |
| EP-3436454-A1 | A CYCLIC COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | Council of Scientific and Industrial Research (IN) | 2019-02-06 | — | — | EP | claimed |
| WO-2017168447-A1 | A CYCLIC COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-10-05 | — | — | WO | claimed |
| US-11002524-B2 | Cyclic compounds and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-05-11 | — | — | US | disclosed |
| US-11002524-B2 | Cyclic compounds and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2021-05-11 | — | — | US | disclosed |
| US-20200249002-A9 | A CYCLIC COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-08-06 | — | — | US | disclosed |
| US-20200249002-A9 | A CYCLIC COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-08-06 | — | — | US | disclosed |
| EP-3436454-A1 | A CYCLIC COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | Council of Scientific and Industrial Research (IN) | 2019-02-06 | — | — | EP | disclosed |
| WO-2017168447-A1 | A CYCLIC COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-10-05 | — | — | WO | disclosed |
| WO-2017168447-A1 | A CYCLIC COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11002524-B2 | Cyclic compounds and process for the preparation thereof | VIP, TREH, CCKAR | TDP1 3566/4885MEN1 500/4885KMT2A 4261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.