Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.61 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.40 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.40 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.38 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.36 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17106862 | 0.87 | POLRMT (0.58) | POLRMTP2RY1P2RY2P2RY11P2RX1 | |
| SCHEMBL19779239 | 0.87 | POLRMT (0.58) | POLRMTP2RY1P2RY2P2RY11P2RX1 | |
| SCHEMBL20960018 | 0.86 | POLRMT (0.58) | POLRMTP2RY1P2RY2P2RY11P2RX1 | |
| SCHEMBL20755989 | 0.86 | POLRMT (0.72) | POLRMTP2RY1P2RY2P2RY11P2RX1 | |
| SCHEMBL20960149 | 0.85 | POLRMT (0.58) | POLRMTP2RY1P2RY2P2RY11P2RX1 | |
| SCHEMBL16699126 | 0.84 | POLRMT (0.64) | POLRMTP2RY1P2RY2P2RY11P2RX1 | |
| SCHEMBL20834806 | 0.82 | POLRMT (0.59) | POLRMTP2RY1P2RY2P2RY11P2RX1 | |
| SCHEMBL25077197 | 0.82 | POLRMT (0.43) | POLRMT | |
| SCHEMBL20834808 | 0.80 | POLRMT (0.56) | POLRMTP2RY1P2RY2P2RY11P2RX1 | |
| SCHEMBL21120428 | 0.80 | POLRMT (0.56) | POLRMTP2RY1P2RY2P2RY11P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9777035-B2 | 4′-substituted nucleoside reverse transcriptase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-10-03 | — | — | US | disclosed |