Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 8/20 | 0.53 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.49 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HTR5A | P47898 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.48 |
| ▸ | HSP90B1 | P14625 | 4/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12269762 | 1.00 | P2RY1 (0.53) | P2RY1P2RY2HRH2HTR5AADORA3 | |
| SCHEMBL16440590 | 0.93 | P2RY1 (0.52) | P2RY1P2RY2HRH2HTR5AADORA3 | |
| SCHEMBL17832220 | 0.93 | P2RY1 (0.53) | P2RY1P2RY2HRH2HTR5AADORA3 | |
| SCHEMBL12269764 | 0.92 | HRH2 (0.49) | P2RY1P2RY2HRH2HTR5AADORA3 | |
| SCHEMBL16440587 | 0.91 | ADORA3 (0.48) | P2RY1P2RY2HRH2HTR5AADORA3 | |
| SCHEMBL12269709 | 0.91 | P2RY1 (0.42) | P2RY1P2RY2HRH2HTR5AADORA3 | |
| SCHEMBL12269827 | 0.88 | P2RY1 (0.40) | P2RY1P2RY2HRH2HTR5AADORA3 | |
| SCHEMBL17830427 | 0.88 | P2RY1 (0.40) | P2RY1P2RY2HRH2HTR5AADORA3 | |
| SCHEMBL12269850 | 0.88 | P2RY1 (0.47) | P2RY1P2RY2HRH2HTR5AADORA3 | |
| SCHEMBL12269994 | 0.86 | HRH2 (0.43) | P2RY1P2RY2HRH2HTR5AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539352-B1 | AMP DERIVATIVES FOR TREATING CARDIAC DISEASES | UNIV CONNECTICUT (US) | 2017-10-04 | — | — | EP | disclosed |