Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9931047 | 0.87 | CCR2 (0.59) | CCR2 | |
| SCHEMBL17329182 | 0.81 | CCR2 (0.63) | CCR2 | |
| SCHEMBL17329190 | 0.79 | CCR2 (0.60) | CCR2 | |
| SCHEMBL17329186 | 0.79 | CCR2 (0.54) | CCR2 | |
| SCHEMBL15227708 | 0.78 | CCR2 (0.70) | CCR2 | |
| SCHEMBL17329232 | 0.78 | CCR2 (0.58) | CCR2 | |
| SCHEMBL9930965 | 0.78 | CCR2 (0.55) | CCR2 | |
| SCHEMBL9931099 | 0.78 | CCR2 (0.63) | CCR2 | |
| SCHEMBL17329180 | 0.78 | CCR2 (0.58) | CCR2 | |
| SCHEMBL17329185 | 0.77 | CCR2 (0.57) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2955173-B1 | 1,2-BIS-SULFONAMIDE DERIVATIVES AS CHEMOKINE RECEPTOR MODULATORS | ALLERGAN INC (US) | 2017-10-04 | — | — | EP | disclosed |