Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 19/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19416294 | 0.92 | TLR8 (0.37) | TLR8TLR7 | |
| SCHEMBL19416304 | 0.87 | ESR1 (0.38) | TLR8TLR7 | |
| SCHEMBL19416431 | 0.87 | TLR8 (0.34) | TLR8TLR7 | |
| SCHEMBL18772079 | 0.87 | TLR8 (0.41) | TLR8TLR7 | |
| SCHEMBL19416387 | 0.87 | TLR8 (0.38) | TLR8TLR7 | |
| SCHEMBL19416533 | 0.86 | TLR8 (0.35) | TLR8TLR7 | |
| SCHEMBL19416470 | 0.85 | TLR8 (0.41) | TLR8TLR7 | |
| SCHEMBL19416289 | 0.84 | TLR8 (0.38) | TLR8TLR7 | |
| SCHEMBL18771975 | 0.83 | TLR8 (0.45) | TLR8TLR7 | |
| SCHEMBL18772082 | 0.83 | TLR8 (0.40) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225623-A1 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Ventirx Pharmaceuticals, Inc. (US) | 2017-10-04 | — | — | EP | disclosed |