Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19416375 | 0.77 | TSHR (0.35) | TSHR | |
| SCHEMBL13896740 | 0.77 | GAA (0.40) | TSHR | |
| SCHEMBL13896724 | 0.77 | MAPT (0.37) | TSHR | |
| SCHEMBL13896742 | 0.74 | MCHR1 (0.35) | TSHR | |
| SCHEMBL12409948 | 0.74 | GRM5 (0.36) | TSHR | |
| SCHEMBL19416374 | 0.73 | MAPT (0.35) | TSHR | |
| SCHEMBL13822591 | 0.73 | KDM4E (0.32) | HCRTR1HCRTR2 | |
| SCHEMBL16790897 | 0.73 | POLB (0.33) | — | |
| SCHEMBL4497174 | 0.69 | CCR4 (0.37) | — | |
| SCHEMBL31538061 | 0.69 | CCR4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709985-B1 | AMINE DERIVATIVES AS POTASSIUM CHANNEL BLOCKERS | BIONOMICS LTD (AU) | 2017-10-04 | — | — | EP | disclosed |