Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31538061 | 1.00 | CCR4 (0.37) | CCR4PIK3CAKMT2AMEN1EDNRA | |
| SCHEMBL15233567 | 0.83 | CCR4 (0.38) | CCR4PIK3CAKMT2AMEN1EDNRA | |
| SCHEMBL1487932 | 0.81 | CCR4 (0.40) | CCR4PIK3CAKMT2AMEN1EDNRA | |
| SCHEMBL4264185 | 0.79 | RECQL (0.40) | PIK3CAKMT2AMEN1HTTRECQL | |
| SCHEMBL5793716 | 0.77 | CCR4 (0.35) | CCR4KMT2AEDNRAHTTRECQL | |
| SCHEMBL14970085 | 0.77 | CCR4 (0.43) | CCR4EDNRA | |
| SCHEMBL12409948 | 0.77 | GRM5 (0.36) | KMT2AMEN1HTTRECQLNPC1 | |
| SCHEMBL20399659 | 0.77 | CCR4 (0.35) | CCR4KMT2AEDNRAHTTRECQL | |
| SCHEMBL12767704 | 0.77 | PIK3CA (0.41) | PIK3CAKMT2AMEN1HTTRECQL | |
| SCHEMBL91464 | 0.77 | LMNA (0.36) | CCR4PIK3CAEDNRAHTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423294-A | Coffee replica made from individual components | 航行食品股份有限公司 | 2022-04-29 | — | — | CN | claimed |
| EP-3353272-A1 | PERFUME COMPOSITIONS | Givaudan SA (CH) | 2018-08-01 | — | — | EP | claimed |
| US-20180187123-A1 | Perfume Compositions | GIVAUDAN S.A. (CH) | 2018-07-05 | — | — | US | claimed |
| WO-2017050971-A1 | PERFUME COMPOSITIONS | GIVAUDAN SA (CH) | 2017-03-30 | — | — | WO | claimed |
| US-20220402917-A1 | COMPOUND AS SMALL MOLECULE INHIBITOR PD-1/PD-L1 AND APPLICATION THEREOF | MEDSHINE DISCOVERY INC. (CN) | 2022-12-22 | — | — | US | disclosed |
| EP-4043461-A1 | COMPOUND AS SMALL MOLECULE INHIBITOR PD-1/PD-L1 AND APPLICATION THEREOF | Medshine Discovery Inc. (CN) | 2022-08-17 | — | — | EP | disclosed |
| WO-2022166991-A1 | INDOLINE COMPOUND | 南京明德新药研发有限公司 | 2022-08-11 | — | — | WO | disclosed |
| WO-2021063404-A1 | COMPOUND AS SMALL MOLECULE INHIBITOR PD-1/PD-L1 AND APPLICATION THEREOF | 南京明德新药研发有限公司 | 2021-04-08 | — | — | WO | disclosed |
| EP-3300500-B9 | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2021-01-13 | — | — | EP | disclosed |
| EP-3541803-B1 | TRIAZOLE PYRIDYL COMPOUNDS AS AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2020-12-23 | — | — | EP | disclosed |
| EP-3300500-B1 | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | AMGEN INC (US) | 2020-02-26 | — | — | EP | disclosed |
| EP-3353272-A1 | PERFUME COMPOSITIONS | Givaudan SA (CH) | 2018-08-01 | — | — | EP | disclosed |
| US-20060116379-A1 | Compounds exhibiting type X sPLA2 inhibiting effect | OGAWA TOMOYUKI | 2006-06-01 | — | — | US | disclosed |
| US-7026318-B2 | Compounds exhibiting X-type sPLA2 inhibiting effect | SHIONOGI & CO., LTD. (JP) | 2006-04-11 | — | — | US | disclosed |
| US-6756376-B1 | PREVENTING FATTY ACID RELEASE | SHIONOGI & CO., LTD. (JP) | 2004-06-29 | — | — | US | disclosed |
| US-20030181454-A1 | Compounds exhibiting x-type spla2 inibiting effect | SHIONOGI & CO., LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
| US-6407104-B1 | Pyrrolo[1,2-a]pyrazine spla2 inhibitor | SHIONOGI & CO., LTD. (JP) | 2002-06-18 | — | — | US | disclosed |
| CN-1303384-A | Pyrrolo [1,2-a] pyrazine sPLA2 inhibitor | SHIONOGI & CO (JP) | 2001-07-11 | — | — | CN | disclosed |
| EP-1066290-A1 | PYRROLO[1,2-a]PYRAZINE sPLA 2 INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999051605-A1 | PYRROLO[1,2-a]PYRAZINE sPLA2 INHIBITOR | SHIONOGI & CO., LTD. (JP) | 1999-10-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220402917-A1 | COMPOUND AS SMALL MOLECULE INHIBITOR PD-1/PD-L1 AND APPLICATION THEREOF | CD274, PDCD1, PDCD1LG2 | CCR4 1025/4885PIK3CA 3237/4885KMT2A 840/4885 |
| US-20030181454-A1 | Compounds exhibiting x-type spla2 inibiting effect | XDH, TPX2, RXFP2 | CCR4 1506/4885PIK3CA 3570/4885KMT2A 1527/4885 |
| US-20060116379-A1 | Compounds exhibiting type X sPLA2 inhibiting effect | XDH, PLA2G12A, CTRB2 | CCR4 2459/4885PIK3CA 3793/4885KMT2A 1255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.