Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | STK17B | O94768 | 1/20 | 0.48 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ATR | Q13535 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16000816 | 0.92 | TRPV1 (0.51) | TRPV1STK17BSTK17AALDH1A1HPGD | |
| SCHEMBL13428494 | 0.80 | STK17B (0.54) | TRPV1STK17BSTK17AALDH1A1HTT | |
| SCHEMBL16000859 | 0.79 | TRPV1 (0.77) | TRPV1STK17BSTK17AALDH1A1MEN1 | |
| SCHEMBL3826302 | 0.76 | STK17B (0.54) | STK17BSTK17AALDH1A1HTTMEN1 | |
| SCHEMBL13428487 | 0.76 | STK17B (0.54) | STK17BSTK17AALDH1A1HPGDHTT | |
| SCHEMBL13977363 | 0.75 | TRPV1 (0.86) | TRPV1ALDH1A1MEN1KMT2ANOTUM | |
| SCHEMBL13861010 | 0.75 | TRPV1 (0.72) | TRPV1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL3220751 | 0.72 | STK17B (0.50) | STK17BSTK17AALDH1A1KDM4EMAPT | |
| SCHEMBL3223820 | 0.72 | ALDH1A1 (0.51) | STK17BSTK17AALDH1A1MEN1KMT2A | |
| SCHEMBL3223809 | 0.72 | ALDH1A1 (0.51) | STK17BSTK17AALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709609-B1 | HETEROCYCLIC COMPOUNDS | SHIONOGI & CO (JP) | 2017-10-04 | — | — | EP | disclosed |