Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 15/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4294944 | 0.89 | TRPV1 (0.42) | TRPV1POLBCYP3A4CYP3A5 | |
| SCHEMBL13977863 | 0.88 | POLB (0.41) | POLBCYP3A4CYP3A5NAMPT | |
| SCHEMBL13977509 | 0.87 | TRPV1 (0.42) | TRPV1POLBNAMPT | |
| SCHEMBL13977891 | 0.87 | TRPV1 (0.41) | TRPV1POLB | |
| SCHEMBL13977336 | 0.86 | NAMPT (0.42) | TRPV1POLBNAMPT | |
| SCHEMBL13977512 | 0.84 | GPR119 (0.43) | TRPV1 | |
| SCHEMBL3804357 | 0.84 | TRPV1 (0.43) | TRPV1 | |
| SCHEMBL9999453 | 0.82 | TRPV1 (0.42) | TRPV1 | |
| SCHEMBL12073206 | 0.82 | TRPV1 (0.42) | TRPV1 | |
| SCHEMBL4553744 | 0.81 | TRPV1 (0.62) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709609-B1 | HETEROCYCLIC COMPOUNDS | SHIONOGI & CO (JP) | 2017-10-04 | — | — | EP | disclosed |