Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 10/20 | 0.55 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | CASP2 | P42575 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31314363 | 0.91 | AHR (0.54) | AHRNR1H2NR1H3MEN1KMT2A | |
| SCHEMBL19417415 | 0.88 | AHR (0.46) | AHRMEN1KMT2AMAPT | |
| SCHEMBL46737 | 0.87 | AHR (0.52) | AHRNR1H2NR1H3MEN1KMT2A | |
| SCHEMBL19417312 | 0.82 | AHR (0.55) | AHRNR1H2NR1H3LMNAMAPT | |
| SCHEMBL19417332 | 0.81 | AHR (0.44) | AHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL19417416 | 0.79 | AHR (0.54) | AHRMEN1KMT2ALMNAMAPT | |
| SCHEMBL31314477 | 0.77 | AHR (0.44) | AHRKDM4EALDH1A1GABRG2GABRB3 | |
| SCHEMBL31314172 | 0.73 | GABRP (0.42) | AHRMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31314293 | 0.73 | CYP2A6 (0.44) | AHRMEN1KMT2AMAPTKDM4E | |
| SCHEMBL30927171 | 0.72 | AHR (1.00) | AHRLMNAMAPTHTTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3225610-A1 | METHOD FOR MANUFACTURING COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2017-10-04 | — | — | EP | disclosed |