Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1940779 | 1.00 | CTSB (0.55) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL1942948 | 1.00 | CTSB (0.55) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL1942687 | 1.00 | CTSB (0.55) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL1942507 | 0.98 | CTSB (0.53) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL1942391 | 0.98 | CTSB (0.53) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL6369432 | 0.94 | CTSB (0.57) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL6800080 | 0.94 | CTSB (0.57) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL6804142 | 0.94 | CTSB (0.58) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL6797924 | 0.94 | CTSB (0.58) | CTSBADRB3ADRA2BADRA2CCYP3A4 | |
| SCHEMBL1941151 | 0.93 | CTSB (0.54) | CTSBADRB3ADRA2BADRA2CCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455809-B1 | INHIBITORS OF HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2011-06-15 | — | — | EP | disclosed |
| US-6867185-B2 | Inhibitors of hepatitis C virus | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-03-15 | — | — | US | disclosed |