Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 4/20 | 1.00 |
| ▸ | APOBEC3A | P31941 | 4/20 | 1.00 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13381127 | 0.77 | POLB (0.62) | CTDSP1APOBEC3AAPOBEC3GPOLBKMT2A | |
| Iodide SCHEMBL11127723 | 0.76 | APOBEC3A (0.61) | CTDSP1APOBEC3AAPOBEC3GPOLBKMT2A | |
| SCHEMBL13381220 | 0.75 | POLB (0.59) | CTDSP1APOBEC3AAPOBEC3GPOLBKMT2A | |
| SCHEMBL10000234 | 0.74 | POLB (0.58) | CTDSP1APOBEC3AAPOBEC3GPOLBKMT2A | |
| SCHEMBL11457323 | 0.74 | POLB (0.58) | CTDSP1APOBEC3AAPOBEC3GPOLBKMT2A | |
| SCHEMBL11075476 | 0.72 | POLB (0.56) | CTDSP1APOBEC3AAPOBEC3GPOLBCHRM5 | |
| SCHEMBL11075475 | 0.72 | POLB (0.56) | CTDSP1APOBEC3AAPOBEC3GPOLBCHRM5 | |
| Hydrochloric Acid SCHEMBL9635896 | 0.69 | CTDSP1 (0.51) | CTDSP1APOBEC3AAPOBEC3GPOLBKMT2A | |
| SCHEMBL11552985 | 0.69 | CTDSP1 (0.50) | CTDSP1APOBEC3AAPOBEC3GPOLBKMT2A | |
| SCHEMBL13380958 | 0.69 | POLB (0.51) | CTDSP1APOBEC3AAPOBEC3GPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283402-A1 | Poly(ADP-Ribose) Polymerase 1 Inhibitors Structurally Unrelated to NAD | INSTITUTE FOR CANCER RESEARCH D/B/A THE RESEARCH INSTITUTE OF FOX CHASE CANCER CENTER | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283402-A1 | Poly(ADP-Ribose) Polymerase 1 Inhibitors Structurally Unrelated to NAD | PARP1, PARP11, PARP14 | CTDSP1 242/4885APOBEC3A 1576/4885APOBEC3G 1563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.