Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 4/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.51 |
| ▸ | APOBEC3A | P31941 | 4/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11554319 | 0.98 | CTDSP1 (0.49) | CTDSP1PABPC1APOBEC3AAPOBEC3GPOLB | |
| SCHEMBL11552985 | 0.95 | CTDSP1 (0.50) | CTDSP1PABPC1APOBEC3AAPOBEC3GPOLB | |
| SCHEMBL19164699 | 0.88 | CTDSP1 (0.44) | CTDSP1PABPC1APOBEC3AAPOBEC3GPOLB | |
| Hydrochloric Acid SCHEMBL3759338 | 0.82 | CTDSP1 (0.36) | CTDSP1PABPC1APOBEC3AAPOBEC3GPOLB | |
| SCHEMBL19410338 | 0.81 | CTDSP1 (0.47) | CTDSP1PABPC1APOBEC3AAPOBEC3GPOLB | |
| Hydrochloric Acid SCHEMBL295168 | 0.80 | THRB (0.51) | CTDSP1PABPC1APOBEC3AAPOBEC3GPOLB | |
| SCHEMBL9118629 | 0.79 | CTDSP1 (0.37) | CTDSP1PABPC1APOBEC3AAPOBEC3GPOLB | |
| Hydrochloric Acid SCHEMBL11552155 | 0.78 | CTDSP1 (0.35) | CTDSP1PABPC1APOBEC3AAPOBEC3GPOLB | |
| SCHEMBL11338454 | 0.77 | THRB (0.53) | CTDSP1PABPC1APOBEC3AAPOBEC3GPOLB | |
| Iodide SCHEMBL30865827 | 0.77 | CTDSP1 (0.50) | CTDSP1PABPC1APOBEC3AAPOBEC3GPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147750-A | Amino group containing polymers; narrow electrostatic charge distribution | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-15 | — | — | US | disclosed |
| US-4149849-A | FIXING ONTO CELLULOSE A HETEROCYCLIC QUATERNARY AMMONIUM EPOXIDE, ANIONIC DYE | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-17 | — | — | US | disclosed |
| US-4035145-A | FIXING AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-12 | — | — | US | disclosed |