Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 4/20 | 0.97 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.97 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19420724 | 1.00 | CTDSP1 (0.97) | CTDSP1PABPC1GAATDP1ALDH1A1 | |
| SCHEMBL19420732 | 0.89 | CTDSP1 (0.78) | CTDSP1PABPC1GAATDP1ALDH1A1 | |
| SCHEMBL13381099 | 0.76 | PABPC1 (0.59) | CTDSP1PABPC1GAAALDH1A1TMEM97 | |
| SCHEMBL18885118 | 0.76 | PABPC1 (0.59) | CTDSP1PABPC1GAAALDH1A1TMEM97 | |
| SCHEMBL13381093 | 0.74 | PABPC1 (0.56) | CTDSP1PABPC1GAAALDH1A1TMEM97 | |
| SCHEMBL19420730 | 0.72 | CTDSP1 (0.56) | CTDSP1PABPC1TDP1APOBEC3AAPOBEC3G | |
| SCHEMBL12943471 | 0.72 | PABPC1 (0.54) | CTDSP1PABPC1GAAALDH1A1TMEM97 | |
| SCHEMBL1487109 | 0.71 | PABPC1 (0.53) | CTDSP1PABPC1GAAALDH1A1TMEM97 | |
| SCHEMBL8325616 | 0.71 | PABPC1 (0.53) | CTDSP1PABPC1GAAALDH1A1TMEM97 | |
| SCHEMBL714617 | 0.71 | PABPC1 (0.53) | CTDSP1PABPC1GAAALDH1A1TMEM97 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283402-A1 | Poly(ADP-Ribose) Polymerase 1 Inhibitors Structurally Unrelated to NAD | INSTITUTE FOR CANCER RESEARCH D/B/A THE RESEARCH INSTITUTE OF FOX CHASE CANCER CENTER | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283402-A1 | Poly(ADP-Ribose) Polymerase 1 Inhibitors Structurally Unrelated to NAD | PARP1, PARP11, PARP14 | CTDSP1 242/4885PABPC1 434/4885GAA 1926/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.