Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPID | Q08752 | 16/20 | 0.45 |
| ▸ | PPIG | Q13427 | 5/20 | 0.37 |
| ▸ | PPIB | P23284 | 5/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19423718 | 1.00 | PPID (0.45) | PPIDPPIGPPIBPOLBMAPK1 | |
| SCHEMBL19429983 | 0.88 | PPID (0.45) | PPIDPPIGPPIBPOLBMEN1 | |
| SCHEMBL19429924 | 0.88 | PPID (0.45) | PPIDPPIGPPIBPOLBMEN1 | |
| SCHEMBL19429945 | 0.86 | PPID (0.47) | PPIDPPIGPPIBPOLBMEN1 | |
| SCHEMBL19423570 | 0.83 | PPID (0.68) | PPIDPPIGPPIB | |
| SCHEMBL19423769 | 0.83 | PPID (0.47) | PPIDPPIGPPIBKMT2A | |
| SCHEMBL19423719 | 0.79 | PPID (0.50) | PPIDPPIGPPIBMEN1NPC1 | |
| SCHEMBL19423577 | 0.79 | PPID (0.50) | PPIDPPIGPPIBMEN1NPC1 | |
| SCHEMBL19429764 | 0.77 | PPID (0.44) | PPIDPPIGPPIBPOLBMEN1 | |
| SCHEMBL19410071 | 0.76 | PPID (0.70) | PPIDPPIGPPIB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017173048-A1 | COMPOUNDS FOR THE INHIBITION OF CYCLOPHILINS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2017-10-05 | — | — | WO | disclosed |