Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19419069 | 0.88 | TSHR (0.41) | TSHRNLRP3ALDH1A1TDP1 | |
| SCHEMBL19419135 | 0.84 | TSHR (0.46) | TSHRNLRP3FAAHALDH1A1TDP1 | |
| SCHEMBL25761264 | 0.74 | TSHR (0.59) | TSHRNLRP3FAAHALDH1A1TDP1 | |
| Water SCHEMBL27528266 | 0.74 | — | — | |
| SCHEMBL28582 | 0.74 | — | — | |
| SCHEMBL19256218 | 0.73 | — | — | |
| SCHEMBL18950544 | 0.73 | — | — | |
| SCHEMBL19419125 | 0.73 | NLRP3 (0.44) | TSHRNLRP3ALDH1A1TDP1 | |
| SCHEMBL22269112 | 0.72 | TSHR (0.50) | TSHRNLRP3ALDH1A1 | |
| SCHEMBL19256236 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170283443-A1 | FLUOROSILICON NITRILE COMPOUNDS | ARKEMA INC. | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170283443-A1 | FLUOROSILICON NITRILE COMPOUNDS | NCL, NOC2L, AFF4 | TSHR 2321/4885NLRP3 4719/4885FAAH 3250/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.