SCHEMBL19424170

SCHEMBL19424170

Oc1cc(O)c2c(c1)OC(c1cc(O)c(O)c(O)c1)C(O)C2c1c(O)cc(O)c2c1OC(c1ccc(O)c(O)c1)C(O)C2

nearest known ligand 0.92

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 3/20 0.92
HSD17B10 Q99714 3/20 0.92
ALOX15 P16050 2/20 0.92
CYP1A2 P05177 1/20 0.92
MMP2 P08253 4/20 0.91
MMP9 P14780 4/20 0.91
PRKD3 O94806 3/20 0.91
PRKCG P05129 3/20 0.91
PRKCB P05771 3/20 0.91
PRKCA P17252 3/20 0.91
PRKCH P24723 3/20 0.91
PRKCI P41743 3/20 0.91
PRKCE Q02156 3/20 0.91
PRKCQ Q04759 3/20 0.91
PRKCZ Q05513 3/20 0.91
PRKCD Q05655 3/20 0.91
PRKD1 Q15139 3/20 0.91
PTGS1 P23219 2/20 0.87
PDE4D Q08499 1/20 0.63
BACE1 P56817 4/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29985642 1.00 SNCA (0.92) SNCAHSD17B10ALOX15CYP1A2MMP2
Procyanidin B2 SCHEMBL14413656 0.96 SNCA (1.00) SNCAHSD17B10ALOX15CYP1A2MMP2
Procyanidin B2 SCHEMBL18685718 0.96 SNCA (1.00) SNCAHSD17B10ALOX15CYP1A2MMP2
Procyanidin B2 SCHEMBL677697 0.96 SNCA (1.00) SNCAHSD17B10ALOX15CYP1A2MMP2
Procyanidin B2 SCHEMBL14626386 0.96 SNCA (1.00) SNCAHSD17B10ALOX15CYP1A2MMP2
Procyanidin B2 SCHEMBL23251016 0.96 SNCA (1.00) SNCAHSD17B10ALOX15CYP1A2MMP2
Procyanidin B2 SCHEMBL14339427 0.96 SNCA (1.00) SNCAHSD17B10ALOX15CYP1A2MMP2
Procyanidin B2 SCHEMBL22043665 0.96 SNCA (1.00) SNCAHSD17B10ALOX15CYP1A2MMP2
Procyanidin B2 SCHEMBL20661403 0.96 SNCA (1.00) SNCAHSD17B10ALOX15CYP1A2MMP2
Procyanidin B2 SCHEMBL15142352 0.96 SNCA (1.00) SNCAHSD17B10ALOX15CYP1A2MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230133290-A1 ACTIVE MIXURE SYMRISE AG (DE) 2023-05-04 US disclosed
US-20230133290-A1 ACTIVE MIXURE SYMRISE AG (DE) 2023-05-04 US disclosed
WO-2017167364-A1 AN ACTIVE MIXTURE SYMRISE AG (DE) 2017-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230133290-A1 ACTIVE MIXURE GUSB, MMP8, IDUA SNCA 4484/4885HSD17B10 454/4885ALOX15 1538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.