Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 11/20 | 0.63 |
| ▸ | BCL2 | P10415 | 13/20 | 0.62 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.61 |
| ▸ | BAD | Q92934 | 2/20 | 0.61 |
| ▸ | MDM4 | O15151 | 1/20 | 0.61 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | BID | P55957 | 1/20 | 0.61 |
| ▸ | BAX | Q07812 | 1/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | ASPH | Q12797 | 1/20 | 0.61 |
| ▸ | BECN1 | Q14457 | 1/20 | 0.61 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.61 |
| ▸ | BBC3 | Q9BXH1 | 1/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2020634 | 0.93 | BCL2L1 (0.63) | BCL2L1BCL2BAK1BADMDM4 | |
| SCHEMBL2022210 | 0.91 | BCL2L1 (0.74) | BCL2L1BCL2BAK1BADMDM4 | |
| SCHEMBL19425240 | 0.89 | BCL2 (0.60) | BCL2L1BCL2BAK1BADMDM4 | |
| SCHEMBL19424249 | 0.88 | BCL2L1 (0.60) | BCL2L1BCL2BAK1BADMDM4 | |
| SCHEMBL19424225 | 0.88 | BCL2L1 (0.65) | BCL2L1BCL2BAK1BADMDM4 | |
| SCHEMBL19424358 | 0.87 | BCL2L1 (0.59) | BCL2L1BCL2 | |
| SCHEMBL19424230 | 0.87 | BCL2L1 (0.70) | BCL2L1BCL2BAK1BADMDM4 | |
| SCHEMBL1540842 | 0.86 | BCL2L1 (0.73) | BCL2L1BCL2BAK1BADMDM4 | |
| SCHEMBL19424318 | 0.86 | BCL2L1 (0.76) | BCL2L1BCL2BAK1BADMDM4 | |
| SCHEMBL19424901 | 0.86 | BCL2L1 (0.74) | BCL2L1BCL2BAK1BADMDM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | UNITY BIOTECHNOLOGY, INC. | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281649-A1 | COMPOUNDS AND THERAPEUTIC USES | TP53, NQO1, SHMT2 | BCL2L1 953/4885BCL2 520/4885BAK1 524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.