Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.67 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.67 |
| ▸ | MGLL | Q99685 | 2/20 | 0.57 |
| ▸ | FABP3 | P05413 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.47 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.47 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.47 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | F7 | P08709 | 3/20 | 0.47 |
| ▸ | F3 | P13726 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11761431 | 1.00 | BCL9 (0.67) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL11761443 | 1.00 | BCL9 (0.67) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL13729888 | 1.00 | BCL9 (0.67) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL13164410 | 1.00 | BCL9 (0.67) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL1942721 | 1.00 | BCL9 (0.67) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL5454330 | 0.99 | BCL9 (0.65) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL13184391 | 0.93 | BCL9 (0.63) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL9615216 | 0.92 | BCL9 (0.57) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL22531036 | 0.92 | BCL9 (0.78) | BCL9CTNNB1MGLLALDH1A1KMT2A | |
| SCHEMBL136672 | 0.92 | BCL9 (0.78) | BCL9CTNNB1MGLLALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2702150-B1 | LIPASE VARIANTS HAVING INCREASED ENZYME SPECIFICITY OR ENHANCED TRANS-SELECTIVITY, AND METHODS OF USE | FRITO LAY TRADING CO GMBH (CH) | 2016-02-10 | — | — | EP | disclosed |
| EP-2702150-A1 | LIPASE VARIANTS HAVING INCREASED ENZYME SPECIFICITY OR ENHANCED TRANS-SELECTIVITY, AND METHODS OF USE | Frito-Lay Trading Company GmbH (CH) | 2014-03-05 | — | — | EP | disclosed |
| WO-2012146935-A1 | LIPASE VARIANTS HAVING INCREASED ENZYME SPECIFICITY OR ENHANCED TRANS-SELECTIVITY, AND METHODS OF USE | FRITO-LAY TRADING COMPANY, GMBH (CH) | 2012-11-01 | — | — | WO | disclosed |
| EP-1476462-B1 | NOVEL FUNGAL LIPASE | PROCTER & GAMBLE (US) | 2011-06-15 | — | — | EP | disclosed |
| EP-1590452-B1 | STABLE LIPASE VARIANTS | COUNCIL SCIENT IND RES (IN) | 2009-06-03 | — | — | EP | disclosed |
| US-7303904-B2 | Stable gene variants of lipases | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2007-12-04 | — | — | US | disclosed |
| CN-1768135-A | Stable lipase variants | COUNCIL SCIENT IND RES (IN) | 2006-05-03 | — | — | CN | disclosed |
| EP-1590452-A2 | STABLE LIPASE VARIANTS | Council of Scientific and Industrial Research (IN) | 2005-11-02 | — | — | EP | disclosed |
| EP-1476462-A4 | NOVEL FUNGAL LIPASE | PROCTER & GAMBLE (US) | 2005-09-28 | — | — | EP | disclosed |
| US-20050196834-A1 | Stable gene variants of lipases | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-09-08 | — | — | US | disclosed |
| US-6897033-B2 | Fungal lipase | THE PROCTER & GAMBLE COMPANY (US) | 2005-05-24 | — | — | US | disclosed |
| EP-1476462-A2 | NOVEL FUNGAL LIPASE | THE PROCTER & GAMBLE COMPANY (US) | 2004-11-17 | — | — | EP | disclosed |
| WO-2004067705-A2 | STABLE LIPASE VARIANTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-08-12 | — | — | WO | disclosed |
| WO-2003070907-A2 | NOVEL FUNGAL LIPASE | THE PROCTER & GAMBLE COMPANY (US) | 2003-08-28 | — | — | WO | disclosed |
| US-20030158385-A1 | Novel fungal lipase | THE PROCTER & GAMBLE COMPANY | 2003-08-21 | — | — | US | disclosed |