Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.65 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.65 |
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | FABP3 | P05413 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | F7 | P08709 | 4/20 | 0.49 |
| ▸ | F3 | P13726 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARD | Q03181 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13729888 | 0.99 | BCL9 (0.67) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL11761443 | 0.99 | BCL9 (0.67) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL11761431 | 0.99 | BCL9 (0.67) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL13164410 | 0.99 | BCL9 (0.67) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL1942721 | 0.99 | BCL9 (0.67) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL1942724 | 0.99 | BCL9 (0.67) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL9615216 | 0.93 | BCL9 (0.57) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL13184391 | 0.91 | BCL9 (0.63) | BCL9CTNNB1MGLLFABP3ALDH1A1 | |
| SCHEMBL22531036 | 0.91 | BCL9 (0.78) | BCL9CTNNB1MGLLALDH1A1PTPN7 | |
| SCHEMBL14401931 | 0.91 | BCL9 (0.78) | BCL9CTNNB1MGLLALDH1A1PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250406-A1 | MUTANT LIPASE AND USE THEREOF | DSM IP ASSETS B.V. (NL) | 2023-08-10 | — | — | US | disclosed |
| US-11667902-B2 | Lipolytic enzyme variants | DSM IP ASSETS B.V. (NL) | 2023-06-06 | — | — | US | disclosed |
| US-20230080079-A1 | MUTANT LIPASE AND USE THEREOF | DSM IP ASSETS B.V. (NL) | 2023-03-16 | — | — | US | disclosed |
| US-20210087542-A1 | LIPOLYTIC ENZYME VARIANTS | DSM IP ASSETS B.V. (NL) | 2021-03-25 | — | — | US | disclosed |
| EP-3794115-A2 | MUTANT LIPASE AND USE THEREOF | DSM IP Assets B.V. (NL) | 2021-03-24 | — | — | EP | disclosed |
| EP-3794114-A2 | MUTANT LIPASE AND USE THEREOF | DSM IP Assets B.V. (NL) | 2021-03-24 | — | — | EP | disclosed |
| US-10918113-B2 | Lipolytic enzyme variants | DSM IP ASSETS B.V. (NL) | 2021-02-16 | — | — | US | disclosed |
| US-10889807-B2 | Lipolytic enzyme variants | DSM IP ASSETS B.V. (NL) | 2021-01-12 | — | — | US | disclosed |
| CN-112135903-A | Mutant lipase and use thereof | 帝斯曼知识产权资产管理有限公司 | 2020-12-25 | — | — | CN | disclosed |
| US-20190335764-A1 | LIPOLYTIC ENZYME VARIANTS | DSM IP ASSETS B.V. (NL) | 2019-11-07 | — | — | US | disclosed |
| US-20190338261-A1 | LIPOLYTIC ENZYME VARIANTS | DSM IP ASSETS B.V. (NL) | 2019-11-07 | — | — | US | disclosed |
| EP-3559221-A1 | LIPOLYTIC ENZYME VARIANTS | DSM IP Assets B.V. (NL) | 2019-10-30 | — | — | EP | disclosed |
| EP-3559222-A1 | LIPOLYTIC ENZYME VARIANTS | DSM IP Assets B.V. (NL) | 2019-10-30 | — | — | EP | disclosed |
| WO-2018114912-A1 | LIPOLYTIC ENZYME VARIANTS | DSM IP ASSETS B.V. (NL) | 2018-06-28 | — | — | WO | disclosed |
| WO-2018114940-A1 | LIPOLYTIC ENZYME VARIANTS | DSM IP ASSETS B.V. (NL) | 2018-06-28 | — | — | WO | disclosed |
| WO-2018114938-A1 | LIPOLYTIC ENZYME VARIANTS | DSM IP ASSETS B.V. (NL) | 2018-06-28 | — | — | WO | disclosed |
| WO-2018114941-A1 | LIPOLYTIC ENZYME VARIANTS | DSM IP ASSETS B.V. (NL) | 2018-06-28 | — | — | WO | disclosed |
| US-20070122862-A1 | Screening for lipolytic enzymes or amidase activity | NOVOZYMES A/S (DK) | 2007-05-31 | — | — | US | disclosed |
| EP-1682671-A1 | SCREENING FOR LIPOLYTIC ENZYME OR AMIDASE ACTIVITY | Novozymes A/S (DK) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005040410-A1 | SCREENING FOR LIPOLYTIC ENZYME OR AMIDASE ACTIVITY | NOVOZYMES A/S (DK) | 2005-05-06 | — | — | WO | disclosed |