Mevalonic Acid

Mevalonic Acid

SCHEMBL1942946

C[C@@](O)(CCO)CC(=O)O.O=P(O)(O)OP(=O)(O)O

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.48
CHRM1 P11229 1/20 0.48
TBXA2R P21731 1/20 0.48
ADRA1A P35348 1/20 0.48
MVD P53602 4/20 0.42
TDP1 Q9NUW8 2/20 0.38
FFAR1 O14842 1/20 0.38
CPT2 P23786 1/20 0.38
FDPS P14324 1/20 0.36
BLM P54132 1/20 0.36
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
PPARD Q03181 1/20 0.33
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mevalonic Acid SCHEMBL25261528 1.00 HMGCR (0.48) HMGCRCHRM1TBXA2RADRA1AMVD
Mevalonic Acid SCHEMBL27658948 0.89 HMGCR (0.56) HMGCRCHRM1TBXA2RADRA1AMVD
Mevalonic Acid SCHEMBL621726 0.89 HMGCR (0.56) HMGCRCHRM1TBXA2RADRA1AMVD
Mevalonic Acid SCHEMBL29575532 0.89 HMGCR (0.56) HMGCRCHRM1TBXA2RADRA1AMVD
Mevalonic Acid SCHEMBL27597534 0.89 HMGCR (0.56) HMGCRCHRM1TBXA2RADRA1AMVD
Mevalonic Acid SCHEMBL28177475 0.85 HMGCR (0.52) HMGCRCHRM1TBXA2RADRA1AMVD
Mevalonic Acid SCHEMBL120276 0.84 HMGCR (0.67) HMGCRCHRM1TBXA2RADRA1ATDP1
Mevalonic Acid SCHEMBL8854071 0.84 HMGCR (0.67) HMGCRCHRM1TBXA2RADRA1ATDP1
Mevalonic Acid SCHEMBL120275 0.84 HMGCR (0.67) HMGCRCHRM1TBXA2RADRA1ATDP1
Mevalonic Acid SCHEMBL18376074 0.84 HMGCR (0.67) HMGCRCHRM1TBXA2RADRA1ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250340908-A1 CO-CULTIVATION SYSTEM AND METHOD FOR SYNTHESIZING TERPENES Oxford University (Suzhou) Science & Technology Co., Ltd. (CN) 2025-11-06 US disclosed
EP-4534648-A1 CO-CULTURE SYSTEM AND METHOD FOR SYNTHESIZING TERPENE Oxford University (Suzhou) Science and Technology CO. LTD (CN) 2025-04-09 EP disclosed
CN-118813433-A Genetically engineered bacterium for producing beta-carotene and preparation method and application thereof 苏州一兮生物技术有限公司 2024-10-22 CN disclosed
CN-118435948-A Application of mevalonic acid in prevention and treatment of cucumber fusarium wilt 扬州大学 2024-08-06 CN disclosed
CN-117778218-A Recombinant yarrowia lipolytica capable of producing abscisic acid in high yield as well as construction method and application thereof 南京工业大学 2024-03-29 CN disclosed
CN-114606146-A Yeast for producing D-limonene and application thereof 江南大学 2022-06-10 CN disclosed
WO-2022044979-A1 EXOGENOUS OPSIN AND CELLS EXPRESSING SAID RHODOPSIN 静岡県公立大学法人 2022-03-03 WO disclosed
CN-103923947-A Method For Producing Alpha- Santalene FIRMENICH & CIE 2014-07-16 CN disclosed
CN-103906834-A Cytochrome p450 and use thereof for the enzymatic oxidation of terpenes FIRMENICH & CIE 2014-07-02 CN disclosed
CN-101978062-B Method for producing alpha-santalene FIRMENICH & CIE 2014-04-02 CN disclosed
US-6872556-B2 Isoprenoid production DSM IP ASSETS B.V. (NL) 2005-03-29 US disclosed
US-20040237147-A1 Modulation of cytokinin activity in plants PIONEER HI-BRED INTERNATIONAL, INC. 2004-11-25 US disclosed
WO-2004090143-A2 MODULATION OF CYTOKININ ACTIVITY IN PLANTS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2004-10-21 WO disclosed
US-20030190734-A1 Isoprenoid production ROCHE VITAMINS, INC. 2003-10-09 US disclosed
US-6586202-B2 Isolated DNA sequence encoding an enzyme in the mevalonate pathway or the pathway from isopentenyl pyrophosphate to farnesyl pyrophosphate. Vectors and plasmids including such DNA are also set forth. The invention also includes host ROCHE VITAMINS, INC. 2003-07-01 US disclosed
US-20030054523-A1 Isoprenoid production ROCHE VITAMINS INC. 2003-03-20 US disclosed
EP-1171619-A1 REGULATED EXPRESSION OF GENES IN PLANT SEEDS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2002-01-16 EP disclosed
US-6284506-B1 MOLECULAR HYBRIDIZATION; CAROTENOID AND ASTAXANTHIN PRODUCTION; GENE EXPRESSION OF MELAVONATE OR ISOPENTENYL TO FARNESYL PYROPHOSPHATE BIOSYNTHETIC ENZYMES ROCHE VITAMINS INC. 2001-09-04 US disclosed
WO-2000063401-A1 REGULATED EXPRESSION OF GENES IN PLANT SEEDS PIONEER HI-BRED INTERNATIONAL, INC. (US) 2000-10-26 WO disclosed
EP-0955363-A2 Dna sequences encoding enzymes involved in production of isoprenoids F. HOFFMANN-LA ROCHE AG (CH) 1999-11-10 EP disclosed