Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 11/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.41 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.41 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31391141 | 0.93 | ACVRL1 (0.49) | ACVRL1MTORRICTORRPTORMAPKAP1 | |
| SCHEMBL16011302 | 0.86 | ACVRL1 (0.58) | ACVRL1CSNK2A2CSNK2A1MTORRICTOR | |
| SCHEMBL16011301 | 0.86 | ACVRL1 (0.58) | ACVRL1CSNK2A2CSNK2A1MTORRICTOR | |
| SCHEMBL19377710 | 0.85 | ACVRL1 (0.44) | ACVRL1MTORRICTORRPTORMAPKAP1 | |
| SCHEMBL19377805 | 0.83 | PIK3CD (0.53) | ACVRL1CSNK2A2CSNK2A1PIK3CD | |
| SCHEMBL19377690 | 0.83 | ACVRL1 (0.61) | ACVRL1MTORRICTORRPTORMAPKAP1 | |
| SCHEMBL19377514 | 0.83 | TYRO3 (0.44) | ACVRL1MTORRICTORRPTORMAPKAP1 | |
| SCHEMBL23834529 | 0.82 | ACVRL1 (0.43) | ACVRL1MTORRICTORRPTORMAPKAP1 | |
| Hydrochloric Acid SCHEMBL19377754 | 0.82 | ACVRL1 (0.60) | ACVRL1MTORRICTORRPTORMAPKAP1 | |
| Hydrochloric Acid SCHEMBL29720772 | 0.82 | ACVRL1 (0.60) | ACVRL1MTORRICTORRPTORMAPKAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017172596-A1 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | INCYTE CORPORATION (US) | 2017-10-05 | — | — | WO | disclosed |