Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVRL1 | P37023 | 8/20 | 0.56 |
| ▸ | TYRO3 | Q06418 | 8/20 | 0.46 |
| ▸ | MERTK | Q12866 | 5/20 | 0.46 |
| ▸ | AXL | P30530 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19429541 | 0.85 | ACVRL1 (0.59) | ACVRL1TYRO3MERTKAXL | |
| SCHEMBL19377753 | 0.82 | MERTK (0.61) | TYRO3MERTKAXL | |
| SCHEMBL25178007 | 0.82 | ACVRL1 (0.70) | ACVRL1TYRO3MERTKAXL | |
| SCHEMBL25178006 | 0.82 | ACVRL1 (0.70) | ACVRL1TYRO3MERTKAXL | |
| SCHEMBL25178822 | 0.79 | ACVRL1 (0.53) | ACVRL1TYRO3MERTKAXL | |
| SCHEMBL19377767 | 0.79 | ACVRL1 (0.58) | ACVRL1TYRO3MERTKAXL | |
| SCHEMBL25178820 | 0.78 | ACVRL1 (0.56) | ACVRL1TYRO3MERTKAXL | |
| SCHEMBL25172263 | 0.77 | ACVRL1 (0.53) | ACVRL1TYRO3MERTKAXL | |
| SCHEMBL19377638 | 0.76 | MERTK (0.54) | ACVRL1TYRO3MERTKAXL | |
| SCHEMBL19429639 | 0.75 | AXL (0.60) | ACVRL1TYRO3MERTKAXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017172596-A1 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | INCYTE CORPORATION (US) | 2017-10-05 | — | — | WO | disclosed |