Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 20/20 | 0.89 |
| ▸ | AXL | P30530 | 2/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19429630 | 0.95 | TYRO3 (0.89) | TYRO3AXL | |
| SCHEMBL29625539 | 0.94 | TYRO3 (1.00) | TYRO3AXL | |
| SCHEMBL19377680 | 0.94 | TYRO3 (1.00) | TYRO3AXL | |
| SCHEMBL31051667 | 0.94 | TYRO3 (1.00) | TYRO3AXL | |
| SCHEMBL19377610 | 0.94 | TYRO3 (1.00) | TYRO3AXL | |
| SCHEMBL19377742 | 0.93 | TYRO3 (1.00) | TYRO3AXL | |
| SCHEMBL29758802 | 0.93 | TYRO3 (1.00) | TYRO3AXL | |
| SCHEMBL19429485 | 0.92 | TYRO3 (0.90) | TYRO3AXL | |
| SCHEMBL19377682 | 0.90 | TYRO3 (1.00) | TYRO3AXL | |
| SCHEMBL29626090 | 0.90 | TYRO3 (1.00) | TYRO3AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017172596-A1 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | INCYTE CORPORATION (US) | 2017-10-05 | — | — | WO | disclosed |