SCHEMBL29626090

SCHEMBL29626090

CC(=O)N1CCC(c2cc(-c3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)c3c(N)ncnn23)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TYRO3 Q06418 20/20 1.00
▸ AXL P30530 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19377682 1.00 TYRO3 (1.00) TYRO3AXL
SCHEMBL19377668 0.95 TYRO3 (1.00) TYRO3
SCHEMBL31067812 0.95 TYRO3 (1.00) TYRO3
SCHEMBL26613629 0.94 TYRO3 (0.89) TYRO3
SCHEMBL19377708 0.93 TYRO3 (1.00) TYRO3AXL
SCHEMBL19377742 0.93 TYRO3 (1.00) TYRO3AXL
SCHEMBL29758802 0.93 TYRO3 (1.00) TYRO3AXL
SCHEMBL19377562 0.93 TYRO3 (1.00) TYRO3AXL
SCHEMBL29625546 0.93 TYRO3 (1.00) TYRO3AXL
SCHEMBL19377622 0.92 TYRO3 (1.00) TYRO3AXL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114456175-B Pyrrolotriazine compounds as TAM inhibitors 因赛特公司 2024-09-03 — — CN claimed
CN-120570893-A Application of small molecular compound in preparation of 3C-like cysteine protease inhibition product 中国人民解放军军事科学院军事医学研究院 2025-09-02 — — CN disclosed
CN-114456175-B Pyrrolotriazine compounds as TAM inhibitors 因赛特公司 2024-09-03 — — CN disclosed
CN-114456176-B Pyrrolotriazine compounds as TAM inhibitors 因赛特公司 2024-08-30 — — CN disclosed
CN-114456176-A Pyrrolotriazine compounds as TAM inhibitors 因赛特公司 2022-05-10 — — CN disclosed
Send feedback