Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 2/20 | 0.54 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.54 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.54 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 2/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.47 |
| ▸ | GABRE | P78334 | 2/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19430539 | 0.90 | GRIN2A (0.56) | GRIN2BGRIN1GRIN2AGPBAR1MEN1 | |
| SCHEMBL20087595 | 0.88 | GRIN2B (0.63) | GRIN2BGRIN1GRIN2AGPBAR1GABRA1 | |
| SCHEMBL20087704 | 0.88 | GRIN2B (0.63) | GRIN2BGRIN1GRIN2AGPBAR1GABRA1 | |
| SCHEMBL26403321 | 0.86 | GPBAR1 (0.64) | GPBAR1 | |
| SCHEMBL19430542 | 0.86 | GPBAR1 (0.64) | GPBAR1 | |
| SCHEMBL25479009 | 0.86 | GPBAR1 (0.64) | GPBAR1 | |
| SCHEMBL20087694 | 0.86 | GPBAR1 (0.64) | GPBAR1 | |
| SCHEMBL20087697 | 0.86 | GPBAR1 (0.64) | GPBAR1 | |
| SCHEMBL19430279 | 0.83 | GPBAR1 (0.63) | GPBAR1MEN1KMT2A | |
| SCHEMBL26401888 | 0.81 | GPBAR1 (0.45) | GRIN2BGRIN1GPBAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017173358-A1 | OXYSTEROLS AND METHODS OF USE THEREOF | SAGE THERAPEUTICS, INC. (US) | 2017-10-05 | — | — | WO | disclosed |