Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156748 | 0.81 | ESR1 (0.48) | KCNH2TMEM97SLC6A2SLC6A3TAAR1 | |
| SCHEMBL6056925 | 0.81 | TSHR (0.43) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL21523212 | 0.78 | — | — | |
| SCHEMBL16250318 | 0.77 | HTR3E (0.44) | KCNH2TMEM97SLC6A2SLC6A3TAAR1 | |
| SCHEMBL2127822 | 0.77 | TAAR1 (0.54) | KCNH2TMEM97SLC6A2SLC6A3TAAR1 | |
| SCHEMBL436099 | 0.76 | AOC3 (0.52) | KCNH2TMEM97SLC6A2SLC6A3TAAR1 | |
| SCHEMBL6056963 | 0.75 | GRIN2D (0.38) | TMEM97SLC6A2SLC6A3HTR2AHTR2B | |
| Ammonia Solution, Strong SCHEMBL10725614 | 0.74 | AOC3 (0.50) | KCNH2TMEM97SLC6A2SLC6A3TAAR1 | |
| SCHEMBL8507908 | 0.73 | IGF1R (0.40) | KCNH2TAAR1HRH1GAACYP1A2 | |
| SCHEMBL21175025 | 0.72 | TAAR1 (0.47) | KCNH2TMEM97SLC6A2SLC6A3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230131867-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | SLOAN KETTERING INST CANCER RES (US) | 2023-04-27 | — | — | US | disclosed |
| US-20170283450-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | MEMORIAL SLOAN-KETTERING INST FOR CANCER RES (US) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230131867-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | LSS, CYP51A1, TLR7 | KCNH2 4715/4885TMEM97 4234/4885SLC6A2 4641/4885 |
| US-20170283450-A1 | TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF | LSS, CYP51A1, TLR7 | KCNH2 4715/4885TMEM97 4234/4885SLC6A2 4641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.