SCHEMBL19430679

SCHEMBL19430679

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nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.67
▸ MAPT P10636 1/20 0.65
▸ POLB P06746 1/20 0.46
▸ GAA P10253 1/20 0.44
▸ TYR P14679 1/20 0.44
▸ SYNJ2 O15056 1/20 0.42
▸ MEN1 O00255 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ SLC28A3 Q9HAS3 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ ALDH1A1 P00352 1/20 0.40
▸ HPGD P15428 1/20 0.40
▸ ACHE P22303 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26192078 1.00 L3MBTL1 (0.67) L3MBTL1MAPTPOLBGAATYR
SCHEMBL24702744 1.00 L3MBTL1 (0.67) L3MBTL1MAPTPOLBGAATYR
SCHEMBL26192479 1.00 L3MBTL1 (0.67) L3MBTL1MAPTPOLBGAATYR
SCHEMBL24702743 1.00 L3MBTL1 (0.67) L3MBTL1MAPTPOLBGAATYR
SCHEMBL20713675 0.98 L3MBTL1 (0.70) L3MBTL1MAPTPOLBGAATYR
SCHEMBL24004406 0.98 L3MBTL1 (0.70) L3MBTL1MAPTPOLBGAATYR
SCHEMBL23266290 0.98 L3MBTL1 (0.70) L3MBTL1MAPTPOLBGAATYR
SCHEMBL20713626 0.98 L3MBTL1 (0.70) L3MBTL1MAPTPOLBGAATYR
SCHEMBL20713629 0.98 L3MBTL1 (0.70) L3MBTL1MAPTPOLBGAATYR
SCHEMBL17703268 0.98 L3MBTL1 (0.70) L3MBTL1MAPTPOLBGAATYR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230131867-A1 TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF SLOAN KETTERING INST CANCER RES (US) 2023-04-27 — — US disclosed
US-20170283450-A1 TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF MEMORIAL SLOAN-KETTERING INST FOR CANCER RES (US) 2017-10-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131867-A1 TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF LSS, CYP51A1, TLR7 L3MBTL1 2235/4885MAPT 4111/4885POLB 826/4885
US-20170283450-A1 TRITERPENE SAPONINS, METHODS OF SYNTHESIS AND USES THEREOF LSS, CYP51A1, TLR7 L3MBTL1 2235/4885MAPT 4111/4885POLB 826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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